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    Answers from an Expert

    Dr. Thomas Kickler, an expert in bloodless surgery as well as conventional, transfusion-based methods, answers common questions about bloodless health care.

    Question

    Bloodless surgery is preferred by individuals who have religious convictions that exclude the use of stored blood products. Besides adhering to an individual's religious beliefs, are there other reasons why bloodless surgery might be the preferred method?

    Dr. Kickler

    Some patients cannot receive blood transfusions because their bodies have already made antibodies against the markers found on some red blood cells. This means that if they are given red blood cells with these markers, their antibodies will automatically attack and destroy the transfused red blood cells. The medical consequences of this reaction (called alloimmunization) can be very serious. It may not be possible to find fully compatible donor blood that will not provoke this reaction.

    Other patients are concerned about the risk of disease transmission and refuse donor transfusions.

    Question

    What conditions are particularly amenable to bloodless techniques?

    Dr. Kickler

    Bloodless techniques are best applied to elective surgical procedures in which there is a predictable amount of blood loss.

    Question

    Are there conditions that might be less amenable to bloodless techniques? How about other factors, such as age and gender, that might make an individual a less promising candidate for bloodless surgery?

    Dr. Kickler

    Patients who are suffering from severe anemia, who are experiencing an active hemorrhage, who are known to have disorders that interfere with blood clotting, who have suffered trauma, or who require a liver transplant are sometimes more difficult to manage, unless they are treated by a team that is very experienced in transfusion-free medicine.

    Question

    Would you expect more complications in patients undergoing bloodless procedures?

    Dr. Kickler

    Yes, although some of these complications are dependent on whether the patient delays in coming to the hospital and initiating treatment, and whether complications of anemia, bleeding, and shock have already set in. Furthermore, the complication rate is dependent upon the specific diagnosis, patient's age, and the presence of other complicating illnesses, such as heart disease.

    Depending upon the specific type of therapy or procedures employed, there may be increased risks. For example, acute normovolemic hemodilution may not be safely done in severely anemic patients, or in patients who have severe heart disease. Treating patients with intravenous iron may result in severe allergic reactions. And using some pharmacologic hemostatic agents may have side effects; Aprontin is associated with allergic reactions, and aminocaproic acid may cause blood clots or a condition called Disseminated Intravascular Coagulation.

    Question

    Should a patient go anywhere in particular to seek bloodless treatment? What should a patient look for in a bloodless surgery center? In a surgeon?

    Dr. Kickler

    It is important that patients who wish to receive bloodless care try to seek treatment in an institution with an organized bloodless medicine program. It is preferable that the institution have practice guidelines in place, and that the medical care team be specifically trained and experienced in bloodless medicine. Surgeons, anesthesiologists, hematologists, and nurses are all integral parts of a successful bloodless medicine program.


    Dr. Thomas Kickler serves on the editorial board of Transfusion and The Journal of Transfusion Alternatives. He is board-certified in three specialties: internal medicine, and hematology. Dr. Kickler is professor of medicine, oncology, and pathology at the Johns Hopkins University School of Medicine.

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    Review Date: May 12, 2005
    Reviewed By: Amy L. Friedman, M.D., Associate Professor of Surgery, Yale University School of Medicine, New Haven, CT. Review provided by VeriMed Healthcare Network.
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