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    Gastroparesis

    Definition

    Gastroparesis is a condition in which the stomach's ability to empty its contents is impaired, unrelated to obstruction.

    Alternative Names

    Gastroparesis diabeticorum; Delayed gastric emptying

    Causes

    The cause of gastroparesis is unknown, but disruption of nerve stimulation to the intestine may be responsible. The condition is a common complication of diabetes and can be a complication of some surgeries. Risk factors for gastroparesis include diabetes, systemic sclerosis, previous vagotomy, previous gastrectomy, visceral neuropathy, and use of anticholinergic medication.

    Symptoms

    Exams and Tests

    Treatment

    Diabetics may improve symptoms of gastroparesis by gaining better control of blood sugar levels. Dietary management with small meals and soft foods (which should be well-cooked and well-chewed) may be of benefit. Medications seem to provide little long-term benefit. Metoclopramide and cholinergic medications can be used. Some cases respond to botulinum toxin ("botox") injection into the pylorus (outlet of the stomach). In some people, gastroenterostomy may be of benefit.

    Outlook (Prognosis)

    Many treatments seem to provide only temporary benefit.

    Possible Complications

    Persistent nausea and vomiting may cause electrolyte imbalances, dehydration, and malnutrition. Diabetics may have serious complications related to poor blood sugar control.

    When to Contact a Medical Professional

    Apply home treatment such as dietary management. Call your provider if symptoms persist or if there are new symptoms.


    Review Date: 5/14/2004
    Reviewed By: Christian Stone, M.D., Division of Gastroenterology, Washington University in St. Louis School of Medicine, St. Louis, MO. Review provided by VeriMed Healthcare Network.
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