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    Henoch-Schonlein purpura

    Definition

    Henoch-Schonlein purpura is a disease that has the symptoms of purple spots on the skin, joint pain, gastrointestinal symptoms, and glomerulonephritis (a type of kidney disorder).

    Alternative Names

    Anaphylactoid purpura; Vascular purpura

    Causes

    Henoch-Schonlein is a type of hypersensitivity vasculitis and inflammatory response within the blood vessel. It is caused by an abnormal response of the immune system. The exact cause for this disorder is unknown.

    The syndrome is usually seen in children, but people of any age may be affected. It is more common in boys than in girls. Many people with Henoch-Schonlein purpura had an upper respiratory illness in the previous weeks.

    Symptoms

    Exams and Tests

    Treatment

    There is no specific treatment for this disorder. Most cases resolve spontaneously without treatment. If symptoms persist, therapy with corticosteroids such as prednisone is usually tried.

    Outlook (Prognosis)

    The disease usually resolves spontaneously without treatment.

    Possible Complications

    • recurrence of symptoms
    • renal impairment (may occur in rare cases)

    When to Contact a Medical Professional

    • Call for an appointment with your health care provider if symptoms of Henoch-Scholnlein purpura develop, particularly if they last for more than a few days.
    • Call your health care provider if low urine output develops after an episode of Henoch-Schonlein purpura.


    Review Date: 8/14/2003
    Reviewed By: Megan E. B. Clowse, M.D., M.P.H., Division of Rheumatology, Johns Hopkins Hospital, Baltimore, MD. Review provided by VeriMed Healthcare Network.
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