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    Waterhouse-Friderichsen syndrome

    Definition

    Waterhouse-Friderichsen syndrome is adrenal gland failure due to bleeding into the adrenal gland. It is caused by severe meningococcal infection and is characterized by acute adrenal gland insufficiency and profound shock. It is fatal if not treated immediately.


    Review Date: 10/27/2005
    Reviewed By: Angelique Green, MD, Assistant Clinical Professor, UCSF School of Medicine, Director of Urgent Care Center, San Francisco General Hospital, San Francisco, CA. Review provided by VeriMed Healthcare Network.
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