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    Histiocyte

    Definition

    Histiocytes are cells of the immune system that ingest foreign antigens to protect against infection. They are fixed, meaning they remain in one part of the body rather than traveling through the bloodstream.

    Histiocytes are found in many organs and connective tissues:

    • Spleen
    • Lymph nodes
    • Brain
    • Liver (Kupffer cells)
    • Breast tissue
    • Alveoli
    • Tonsils
    • Serous cavities
    • Placenta

    Histiocytosis involves an abnormal number of histiocytes and may affect the lungs (alveoli), the bones, or the lymphatic system.

    Alternative Names

    Macrophage


    Review Date: 10/23/2004
    Reviewed By: Kevin Pho, M.D., Attending, Internal Medicine, Boston VA Medical Center, Boston, MA. Review provided by VeriMed Healthcare Network.
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