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    Acetaminophen and codeine overdose

    Definition

    This poisoning is from taking an excessive amount of acetaminophen (Tylenol) with codeine.

    Alternative Names

    Tylenol # 3 overdose; Phenaphen with codeine overdose; Tylenol with codeine overdose

    Poisonous Ingredient

    Acetaminophen combined with codeine

    Where Found

    Acetaminophen with codeine is a prescription painkiller. It is commonly called Tylenol #3. The drug may be habit forming, which means it is a narcotic.

    Note: This list may not be all inclusive.

    Symptoms

    Home Care

    Seek immediate emergency medical help. This type of overdose can cause death.

    DO NOT MAKE THE PERSON THROW UP.

    Before Calling Emergency

    Determine the following information:

    • Patient's age, weight, and condition
    • Name of the product (as well as the ingredients and strength, if known)
    • Time it was swallowed
    • Amount swallowed
    • If the medication was prescribed for the patient

    The National Poison Control Center (1-800-222-1222) can be called from anywhere in the United States. This national hotline number will let you talk to experts in poisoning. They will give you further instructions.

    This is a free and confidential service. All local poison control centers in the U.S. use this national number. You should call if you have any questions about poisoning or poison prevention. It does NOT need to be an emergency. You can call for any reason, 24 hours a day, 7 days a week.

    Take the container with you to the emergency room.

    What to Expect at the Emergency Room

    The health care provider will measure and monitor the patient's vital signs, including temperature, pulse, breathing rate, and blood pressure.

    The patient may be admitted to the hospital, and may receive:

    • Fluids
    • Medicines to treat symptoms
    • Activated charcoal
    • A nasogastric (NG) tube thru the nose into the stomach to empty the stomach (gastric lavage)   
    • Artificial respiration
    • A counteracting drug called naloxone (multiple doses may be needed)

    If there is a high level of acetaminophen in the blood, the patient will be given N-Acetyl cysteine. Without this counteracting drug, called an antidote, deadly liver failure will occur.

    Outlook (Prognosis)

    If medicine to reverse the poisoning (an antidote) can be given, recovery from an acute overdose often occurs within 24-48 hours.


    Review Date: 2/10/2006
    Reviewed By: Janeen R. Azare, PhD, MSPH, Department of Medicine, Memorial Sloan-KetteringCancer Center, New York, NY. Review provided by VeriMed Healthcare Network.
    The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.
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