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    Corneal transplant

    Definition

    A corneal transplant is surgery to replace the clear surface on the front of the eye (the cornea).

    Alternative Names

    Keratoplasty; Penetrating keratoplasty

    Description

    Most corneal transplant operations are done under local anesthesia on an outpatient basis. This means that the patient is awake but an injection is given to make the eye completely numb. There is no pain.

    The corneal tissue for transplantation is taken from a donor shortly after death with the permission of the next of kin. Though most transplant procedures carry the risk of rejection of the transplant tissue or organ, the cornea has very limited blood supply, which greatly reduces this risk. Most corneal transplants function extremely well for many years.

    Why the Procedure is Performed

    Corneal transplantation is recommended for:

    • inherited corneal thinning (keratoconus) with visual distortion
    • scarring of the cornea from severe infections or injuries
    • inherited or acquired corneal clouding (Fuch's dystrophy) with visual loss

    Risks

    The risks for any anesthesia are:

    • reactions to medications
    • problems breathing
    The risks for any surgery are:
    • bleeding, but this is a rare complication since the cornea normally has no blood vessels
    • infection

    Outlook (Prognosis)

    Full visual recovery takes a long time (up to a year), but most patients with successful corneal transplants will enjoy good vision for many years, or even a lifetime.

    Recovery

    Follow your doctor's instructions about limited activity after surgery. Rejection of transplanted tissue may occur in a minority of patients. You must carefully follow your doctor's instructions for use of eye drops which prevent or control this.


    Review Date: 4/11/2005
    Reviewed By: Edward B. Feinberg, M.D., M.P.H., Department of Ophthalmology, Boston University School of Medicine, Boston, MA. Review provided by VeriMed Healthcare Network.
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