The stool guiac test is a test that detects the presence of hidden (occult) blood in the stool (bowel movement). The stool guaiac is the most common form of fecal occult blood test (FOBT) in use today.

If the test is performed in an office or hospital, then stool may be collected by a doctor during a rectal examination.

If the test is performed at home, a stool sample from three consecutive bowel movements is collected, smeared on a card, and mailed to a laboratory for processing. In order to ensure the accuracy of the guaiac test, follow the manufacturer's instructions on how to collect the stool.

There are many ways to collect the samples. You can catch the stool on plastic wrap that is loosely placed over the toilet bowl and held in place by the toilet seat. Then put the sample in a clean container. One test kit supplies a special toilet tissue that you use to collect the sample, then put the sample in a clean container. Do not sample stool specimen from within the toilet bowl water, as this can cause measurement errors.

For infants and young children wearing diapers, you can line the diaper with plastic wrap. If the plastic wrap is positioned so that it isolates the stool from any urine output, mixing of urine and stool can be prevented for a better sample.

Laboratory procedures may vary. In one type of test, a small sample of stool is placed on a paper card. A drop or two of testing solution is applied to the opposite side of the card. A color change indicates the presence of blood in the stool.

Do not consume red meat, any blood-containing food, cantaloupe, uncooked broccoli, turnip, radish, or horseradish for 3 days prior to the test.

You may need to discontinue drugs that can interfere with the test such as vitamin C and aspirin if possible. Check with your health care provider regarding medication changes that may be necessary. Never discontinue or decrease any medication without consulting your health care provider.

There is no discomfort when performed at home, because this test involves normal bowel functions. If stool is collected during a rectal exam, then there may be brief discomfort in the anal canal and rectum.

This test is a screening test to detect blood in the gastrointestinal tract.

A negative test result is normal.

Abnormal results may indicate:

• Colon polyps
• Colon cancer or other gastrointestinal (GI) tumors
• Esophagitis
• Gastritis
• GI trauma or bleeding from recent GI surgery
• Hemorrhoids
• Inflammatory bowel disease
• Peptic ulcer
• Angiodysplasia of the GI tract
• GI infections
• Esophageal varices and portal hypertensive gastropathy

Additional non-GI related causes of positive guaiac test may include:

• Nose bleed
• Coughing up blood

There can be false-positive and false-negative results. Using proper stool collection technique, avoiding certain drugs, and observing dietary restrictions can minimize these measurement errors.