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Nasal mucosal biopsy
Definition
A nasal mucosal biopsy is surgery in which a small piece of tissue is removed from the lining of the nose and checked for disease.
Alternative Names
How the Test is Performed
A pain-killer is sprayed into the nose. In some cases, a numbing shot may be used. A small piece of the tissue that appears abnormal is removed and checked for problems in the laboratory.
How to Prepare for the Test
No special preparation is necessary. You may be asked to fast for a few hours before the biopsy.
How the Test Will Feel
There may feelings of pressure or tugging during removal of the tissue. After the numbness wears off, the area may be sore for a few days. If there is bleeding, cautery (sealing of blood vessels with electric current or laser) may be needed.
Why the Test is Performed
Nasal mucosal biopsy is usually done when abnormal tissue is seen during examination of the nose. It may also be done when problems affecting the mucosal tissue of the nose are suspected.
Normal Results
There is normal mucosal tissue, with no abnormal growths or tissues.
What Abnormal Results Mean
- Necrotizing granuloma (granular tumor)
- Wegener's disease
- Nasal polyps
- Nasal tumors
- Sarcoid
- Infections (tuberculosis, fungal)
Risks
- Infection
- Bleeding from the biopsy site
Considerations
Avoid blowing your nose after the biopsy.
Reviewed By: Kevin Fung, M.D., FRCS(C), Department of Otolaryngology, University of Western Ontario, London, Ontario, Canada. Review provided by VeriMed Healthcare Network.
