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Drugs that may cause impotence
Alternative Names
Information
Various medications and recreational drugs can have an affect on sexual arousal and sexual performance. It should be noted that what causes impotence in one man may not affect another.
If you suspect that a medication you are taking is having a negative effect on sexual performance, discuss the matter with your health care provider. NEVER stop taking any medication without first consulting your health care provider, because some medications can produce life-threatening reactions if they are not tapered or switched appropriately.
The following is a list of medications and non-prescription drugs that may cause impotence:
Antidepressant and other psychiatric medications:
- Amitriptyline (Elavil)
- Buspirone (Buspar)
- Chlordiazepoxide (Librium)
- Chlorpromazine (Thorazine)
- Clorazepate (Tranxene)
- Desipramine (Norpramin)
- Diazepam (Valium)
- Doxepin (Sinequan)
- Fluoxetine (Prozac)
- Fluphenazine (Prolixin)
- Imipramine (Tofranil)
- Lorazepam (Ativan)
- Meprobamate (Equanil)
- Mesoridazine (Serentil)
- Nortriptyline (Pamelor)
- Oxazepam (Serax)
- Phenelzine (Nardil)
- Phenytoin (Dilantin)
- Thioridazine (Mellaril)
- Thiothixene (Navane)
- Tranylcypromine (Parnate)
- Trifluoperazine (Stelazine)
- Dimenhydrinate (Dramamine)
- Diphenhydramine (Benadryl)
- Hydroxyzine (Vistaril)
- Meclizine (Antivert)
- Promethazine (Phenergan)
- Atenolol (Tenormin)
- Bethanidine
- Chlorothiazide (Diuril)
- Chlorthalidone (Hygroton)
- Clonidine (Catapres)
- Enalapril (Vasotec)
- Guanabenz (Wytensin)
- Guanethidine (Ismelin)
- Guanfacine (Tenex)
- Haloperidol (Haldol)
- Hydralazine (Apresoline)
- Hydrochlorothiazide (Esidrix)
- Labetalol (Normodyne)
- Methyldopa (Aldomet)
- Metoprolol (Lopressor)
- Minoxidil (Loniten)
- Phenoxybenzamine (Dibenzyline)
- Phentolamine (Regitine)
- Prazosin (Minipress)
- Propranolol (Inderal)
- Reserpine (Serpasil)
- Spironolactone (Aldactone)
- Triamterene (Maxide)
- Verapamil (Calan)
Among the anti-hypertensive medications, thiazides are the most common cause of ED, followed by beta-blockers. Alpha-blockers are, in general, less likely to cause this problem.
Parkinson's disease medications:- Benztropine (Cogentin)
- Biperiden (Akineton)
- Bromocriptine (Parlodel)
- Levodopa (Sinemet)
- Procyclidine (Kemadrin)
- Trihexyphenidyl (Artane)
- Antiandrogens (Casodex, Flutamide, Nilutamide)
- Busulfan (Myleran)
- Cyclophosphamide (Cytoxan)
- Ketoconazole
- LHRH agonists (Lupron, Zoladex)
Other medications:
- Aminocaproic acid (Amicar)
- Atropine
- Clofibrate (Atromid-S)
- Cyclobenzaprine (Flexeril)
- Cyproterone
- Digoxin (Lanoxin)
- Disopyramide (Norpace)
- Estrogen
- Finesteride (Propecia, Proscar)
- Furazolidone (Furoxone)
- H2 Blockers (Tegamet, Zantac, Pepcid)
- Indomethacin (Indocin)
- Lipid lowering-agents
- Licorice
- Metoclopramide (Reglan)
- NSAIDs (Ibuprofen, etc.)
- Orphenadrine (Norflex)
- Prochlorperazine (Compazine)
Opiate analgesics (painkillers)
- Morphine
- Methadone
- Fentanyl (Innovar)
- Meperidine (Demerol)
- Codeine
- Oxycodone (Oxycontin, Percodan)
- Hydromorphone (Dilaudid)
Recreational Drugs:
Reviewed By: Scott M. Gilbert, M.D., Department of Urology, Columbia-Presbyterian Medical Center, New York, NY. Review provided by VeriMed Healthcare Network.
